NFKBIB (I-kappa-B-beta, Nuclear factor of kappa light polypeptide gene enhancer in B Cells inhibitor, beta)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

NFKBIB (I-kappa-B-beta, Nuclear factor of kappa light polypeptide gene enhancer in B Cells inhibitor, beta)

catalog :

030491

quantity :

100 ul

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

13B569

reactivity :

human

product information

Catalog Number :

030491

Product wo Prefix :

NFKBIB (I-kappa-B-beta, Nuclear factor of kappa light polypeptide gene enhancer in B Cells inhibitor, beta)

Host :

mouse

Product Type :

Mab

Category :

Antibodies

Size1 :

100 ul

Clone # USB :

13B569

Isotype :

IgG1

Desc1 :

Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further IKBA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.Tissue specificity: Expressed in all tissues examined. Applications: Western Bloting: 1:500-1:2000. ELISA: Suggested dilution 1:10000. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

IKBB; TRIP9; NFKBIB

Immunogen :

Purified recombinant fragment of human NFKBIB expressed in E. coli.

Specificity :

Human

Purity :

Ascites

Form :

Ascites fluid, 0.03% sodium azide.

Concentration :

Not determined

Desc2 :

Product Type: Mab Isotype: IgG1 Clone No: 13B569 Host: mouse Source: human Concentration: Not determined Form: Ascites fluid, 0.03% sodium azide. Purity: Ascites Immunogen: Purified recombinant fragment of human NFKBIB expressed in E. coli. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

1. Mol Cell Biol. 2004 Apr;24(7):3048-56. 2. J Biol Chem. 2004 Oct 15;279(42):44030-8. 3. J Bone Miner Res. 2009 Dec;24(12):2039-49.