MBP | US Biological 030433 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

MBP

catalog :

030433

quantity :

100 ul

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

13B511

reactivity :

human

product information

Catalog Number :

030433

Product wo Prefix :

MBP

Host :

mouse

Product Type :

Mab

Category :

Antibodies

Size1 :

100 ul

Clone # USB :

13B511

Isotype :

IgG1

Desc1 :

The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called "Golli-MBP") that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes. Applications: Suitable for use in Flow Cytometry, ELISA, Western Blot, Immunohistochemistry and Immunocytochemistry. Other applications not tested. Recommended Dilutions: Flow Cytometry: 1:200-1:400 ELISA: 1:10,000 Western Blot: 1:500-1:2000 Immunohistochemistry: 1:200-1:1000 Immunocytochemistry: 1:200-1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

MGC99675

Immunogen :

Purified recombinant fragment of human MBP expressed in E. coli

Specificity :

Recognizes human MBP.

Purity :

Ascites

Form :

Supplied as a liquid, 0.03% sodium azide

Concentration :

Not Determined

Desc2 :

Product Type: Mab Isotype: IgG1 Clone No: 13B511 Host: mouse Source: human Concentration: Not Determined Form: Supplied as a liquid, 0.03% sodium azide Purity: Ascites Immunogen: Purified recombinant fragment of human MBP expressed in E. coli Specificity: Recognizes human MBP. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E FC IC IHC WB

Storage Temperature :

-20°C

Reference :

1. Cancer Epidemiol Biomarkers Prev. 2009 May;18(5):1651-8. 2. Biochemistry. 2009 Jun 9;48(22):4720-7