MAP2K6 (Mitogen-activated protein kinase kinase 6) | US Biological 030418 product information

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product summary

company name :

US Biological

product type :

antibody

product name :

MAP2K6 (Mitogen-activated protein kinase kinase 6)

catalog :

030418

quantity :

100 ul

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

13B496

reactivity :

human

product information

Catalog Number :

030418

Product wo Prefix :

MAP2K6 (Mitogen-activated protein kinase kinase 6)

Host :

mouse

Product Type :

Mab

Category :

Antibodies

Size1 :

100 ul

Clone # USB :

13B496

Isotype :

IgG1

Desc1 :

This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. Tissue specificity: Isoform 2 is only expressed in skeletal muscle. Isoform 1, on the other hand, is found in skeletal muscle, heart, and in lesser extent in liver or pancreas . Applications: Western Bloting: 1:500-1:2000. Immunofluorescence: 1:200-1:1000. Flow cytometry: 1:200-1:400. ELISA: Suggested dilution 1:10000. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Hu Mo

Alternate Name :

MEK6; MKK6; MAPKK6; PRKMK6; SAPKK3; MAP2K6

Immunogen :

Purified recombinant fragment of human MAP2K6 expressed in E. coli.

Specificity :

Human, Mouse

Purity :

Ascites

Form :

Ascites fluid, 0.03% sodium azide.

Concentration :

Not determined

Desc2 :

Product Type: Mab Isotype: IgG1 Clone No: 13B496 Host: mouse Source: human Concentration: Not determined Form: Ascites fluid, 0.03% sodium azide. Purity: Ascites Immunogen: Purified recombinant fragment of human MAP2K6 expressed in E. coli. Specificity: Human, Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E FC WB

Storage Temperature :

-20°C

Reference :

1. J Mol Med. 2008 Apr;86(4):485-90. 2. Blood. 2007 Jan 1;109(1):185-93.