LSD1/AOF2 (lysine (K)-specific demethylase 1A, Lysine-specific histone demethylase 1A)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

LSD1/AOF2 (lysine (K)-specific demethylase 1A, Lysine-specific histone demethylase 1A)

catalog :

030408

quantity :

100 ul

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

13B486

reactivity :

human

product information

Catalog Number :

030408

Product wo Prefix :

LSD1/AOF2 (lysine (K)-specific demethylase 1A, Lysine-specific histone demethylase 1A)

Host :

mouse

Product Type :

Mab

Category :

Antibodies

Size1 :

100 ul

Clone # USB :

13B486

Isotype :

IgG1

Desc1 :

The amine oxidase domain 2 (AOF2) gene encodes a nuclear protein (LSD1, ~95kD) containing a Swirm domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. LSD1 is a chromatin-modifying enzyme, which serve as a docking module for the stabilization of the associated corepressor complex (es) on chromatin. Applications: Western Bloting: 1:500-1:2000. Immunofluorescence: 1:200-1:1000. ELISA: Suggested dilution 1:10000. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Hu Mk Mo

Alternate Name :

KDM1; LSD1; AOF2

Immunogen :

Purified recombinant fragment of human LSD1 expressed in E. coli.

Specificity :

Human, Mouse, Monkey

Purity :

Ascites

Form :

Ascites fluid, 0.03% sodium azide.

Concentration :

Not determined

Desc2 :

Product Type: Mab Isotype: IgG1 Clone No: 13B486 Host: mouse Source: human Concentration: Not determined Form: Ascites fluid, 0.03% sodium azide. Purity: Ascites Immunogen: Purified recombinant fragment of human LSD1 expressed in E. coli. Specificity: Human, Mouse, Monkey Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

1. Shi YJ, et.al Mol Cell. 2005 Sep 16;19(6):857-64. 2. Metzger E, et.al Nature. 2005 Sep 15;437(7057):436-9.