KIT | US Biological 030370 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

KIT

catalog :

030370

quantity :

100 ul

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

13B448

reactivity :

human

product information

Catalog Number :

030370

Product wo Prefix :

KIT

Host :

mouse

Product Type :

Mab

Category :

Antibodies

Size1 :

100 ul

Clone # USB :

13B448

Isotype :

IgG1

Desc1 :

The c-Kit proto-oncogene is a member of the receptor tyrosine kinase family and, more specifically, is closely related to the platelet derived growth factor receptor (PDGFR). c-Kit, the normal cellular homolog of the HZ4-feline sarcoma virus transforming gene (v-Kit), encodes a transmembrane receptor. c-Kit regulates a variety of biological responses including chemotaxis, cell prolif- eration, apoptosis and adhesion. c-Kit is also identical with the product of the W locus in mice and, as such, is integral to the development of mast cells and hematopoiesis. The ligand for the c-Kit receptor (KL) has been identified and is encoded at the murine steel (SI) locus. Kit is the human homolog of the proto- oncogene c-Kit. Mutations in Kit are integral for tumor growth and progression in various cancers. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications have not been tested. Recommended Dilutions: Western Blot: 1:500-1:2000. Immunohistochemistry: 1:200-1:1000. ELISA: 1:10,000. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

PBT; SCFR; C-Kit; CD117

Immunogen :

Purified recombinant protein fragment of human KIT expressed in E. coli.

Specificity :

Recognizes human KIT

Purity :

Ascites

Form :

Supplied as a liquid 0.03% sodium azide.

Concentration :

Not determined

Desc2 :

Product Type: Mab Isotype: IgG1 Clone No: 13B448 Host: mouse Source: human Concentration: Not determined Form: Supplied as a liquid 0.03% sodium azide. Purity: Ascites Immunogen: Purified recombinant protein fragment of human KIT expressed in E. coli. Specificity: Recognizes human KIT Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IHC WB

Storage Temperature :

-20°C

Reference :

1. Curr Hematol Malig Rep. 2009 Apr;4(2):77-82. 2. Georgian Med News. 2010 Mar;(180):13-9

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/11/030370_1.jpg

Picture4 Text :

Immunohistochemical analysis of paraffin-embedded gastrointestinal stromal tumor using 030370 with DAB staining.