GRK2 (Beta-adrenergic receptor kinase 1, ADRBK1, G-protein coupled receptor kinase 2)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

GRK2 (Beta-adrenergic receptor kinase 1, ADRBK1, G-protein coupled receptor kinase 2)

catalog :

030276

quantity :

100 ul

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

13B354

reactivity :

human

product information

Catalog Number :

030276

Product wo Prefix :

GRK2 (Beta-adrenergic receptor kinase 1, ADRBK1, G-protein coupled receptor kinase 2)

Host :

mouse

Product Type :

Mab

Category :

Antibodies

Size1 :

100 ul

Clone # USB :

13B354

Isotype :

IgG1

Desc1 :

The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. (provided by RefSeq)Tissue specificity: Expressed in peripheral blood leukocytes Applications: Western Bloting: 1:500-1:2000. Immunohistochemistry: 1:200-1:1000. Immunofluorescence: 1:200-1:1000. ELISA: Suggested dilution 1:10000. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Hu Mk Mo Rt

Alternate Name :

GRK2; BARK1; FLJ16718; BETA-ARK1; ADRBK1

Immunogen :

Purified recombinant fragment of human GRK2 expressed in E. coli.

Specificity :

Human, Mouse, Rat, Monkey

Purity :

Ascites

Form :

Ascites fluid, 0.03% sodium azide.

Concentration :

Not determined

Desc2 :

Product Type: Mab Isotype: IgG1 Clone No: 13B354 Host: mouse Source: human Concentration: Not determined Form: Ascites fluid, 0.03% sodium azide. Purity: Ascites Immunogen: Purified recombinant fragment of human GRK2 expressed in E. coli. Specificity: Human, Mouse, Rat, Monkey Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IHC WB

Storage Temperature :

-20°C

Reference :

1. Mol Biol Cell. 2008 Jul;19(7):2973-83. 2. Biochemistry. 2009 May 26;48(20):4285-93.