GFRA1 (GDNF Family Receptor alpha-1, GDNF Receptor alpha-1, GDNFR-alpha-1, GFR-alpha-1, RET Ligand 1, TGF-beta-related Neurotrophic Factor Receptor 1, GDNFRA, RETL1, TRNR1)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

GFRA1 (GDNF Family Receptor alpha-1, GDNF Receptor alpha-1, GDNFR-alpha-1, GFR-alpha-1, RET Ligand 1, TGF-beta-related Neurotrophic Factor Receptor 1, GDNFRA, RETL1, TRNR1)

catalog :

029787

quantity :

100 ug

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

029787

Product wo Prefix :

GFRA1 (GDNF Family Receptor alpha-1, GDNF Receptor alpha-1, GDNFR-alpha-1, GFR-alpha-1, RET Ligand 1, TGF-beta-related Neurotrophic Factor Receptor 1, GDNFRA, RETL1, TRNR1)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

100 ug

Isotype :

IgG

Desc1 :

Glial cell line-derived neurotrophic factor (GDNF) is a potent survival factor for central and peripheral neurons and is essential for the development of kidneys and the enteric nerves system. Physiological responses to GDNF require the presence of a novel glycosylphosphadidylinositol linked protein GDNFRa, which is a cell surface receptor for GDNF. The cDNA encoding GDNFRa from human, rat, chicken and mouse have been cloned recently. GDNFRa was also termed Ret ligand 1 (RETL1) or TGF-b-related neurotrophic factor receptor 1 (TrnR1) and nominated as GFRa-1 recently. GFRa-1 binds GDNF specifically and mediates activation of the Ret protein tyrosine kinase (PTK). Thus, GDNF, GFRa and the Ret PTK from a complex to transduce GDNF signal and to mediate GDNF function. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5-4ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Hu Mo Rt

Immunogen :

Synthetic peptide corresponding to aa369-382 from human GFRalpha-1.

Specificity :

Recognizes human GFRalpha-1. Species Crossreactivity: mouse and rat.

Purity :

Purified by immunoaffinity chromatography

Form :

Supplied as a liquid in PBS, pH 7.2, 0.5% BSA, 0.01% thimerosal, 30% glycerol.

Concentration :

~0.5mg/ml

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: ~0.5mg/ml Form: Supplied as a liquid in PBS, pH 7.2, 0.5% BSA, 0.01% thimerosal, 30% glycerol. Purity: Purified by immunoaffinity chromatography. Immunogen: Synthetic peptide corresponding to aa369-382 from human GFRalpha-1. Specificity: Recognizes human GFRalpha-1. Species Crossreactivity: mouse and rat. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

Storage Temperature :

-20°C