antibody

Histone H2B Type 1-C/E/F/G/I (Histone H2B.1 A, Histone H2B.a, H2B/a, Histone H2B.g, H2B/g, Histone H2B.h, H2B/h, Histone H2B.k, H2B/k, Histone H2B.l, H2B/l, HIST1H2BC, H2BFL, HIST1H2BE, H2BFH, HIST1H2BF, H2BFG, HIST1H2BG, H2BFA, HIST1H2BI, H2BFK) (F

029185

100 ug

polyclonal

domestic rabbit

FITC

Histone H2B Type 1-C/E/F/G/I (Histone H2B.1 A, Histone H2B.a, H2B/a, Histone H2B.g, H2B/g, Histone H2B.h, H2B/h, Histone H2B.k, H2B/k, Histone H2B.l, H2B/l, HIST1H2BC, H2BFL, HIST1H2BE, H2BFH, HIST1H2BF, H2BFG, HIST1H2BG, H2BFA, HIST1H2BI, H2BFK) (FITC)

www.usbio.net/antibodies/029185/Histone-H2B-Type-1CEFGI-Histone-H2B1-A-Histone-H2Ba-H2Ba-Histone-H2Bg-H2Bg-Histone-H2Bh-H2Bh-Histone-H2Bk-H2Bk-Histone-H2Bl-H2Bl-HIST1H2BC-H2BFL-HIST1H2BE-H2BFH-HIST1H2BF-H2BFG-HIST1H2BG-H2BFA-HIST1H2BI-H2BFK-FITC

rabbit

Pab

FITC

Antibodies

100 ug

IgG

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid. Applications:. Suitable for use in FLISA and Western Blot. Other applications not tested. Recommended Dilution:. Optimal dilutions to be determined by the researcher. Storage and Stability:. May be stored at 4 C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 C. Aliquots are stable for 12 months at -20 C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. FITC conjugates are sensitive to light.

Hu

Recombinant corresponding to human Histone H2B Type 1-C/E/F/G/I.

Recognizes human Histone H2B Type 1-C/E/F/G/I.

Purified by Protein G affinity chromatography.

Supplied as a liquid in 0.01M PBS, PH 7.4, 0.03% Proclin 300, 50% glycerol. Labeled with fluorescein isothiocyanate (FITC).

As reported

Product Type: Pab. Isotype: IgG. Host: rabbit. Source: human. Concentration: As reported. Form: Supplied as a liquid in 0.01M PBS, PH 7.4, 0.03% Proclin 300, 50% glycerol. Labeled with fluorescein isothiocyanate (FITC). Purity: Purified by Protein G affinity chromatography. Immunogen: Recombinant corresponding to human Histone H2B Type 1-C/E/F/G/I. Specificity: Recognizes human Histone H2B Type 1-C/E/F/G/I. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

FL WB

-20 C

1. "Isolation and characterization of two human H1 histone genes within clusters of core histone genes." Albig W., Kardalinou E., Drabent B., Zimmer A., Doenecke D. Genomics 10:940-948 (1991). 2. "Human histone gene organization: nonregular arrangement within a large cluster." Albig W., Kioschis P., Poustka A., Meergans K., Doenecke D. Genomics 40:314-322 (1997). 3. "The human and mouse replication-dependent histone genes." Marzluff W.F., Gongidi P., Woods K.R., Jin J., Maltais L.J. Genomics 80:487-498 (2002). 4. "The DNA sequence and analysis of human chromosome 6." Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L., Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E., Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R., Almeida J.P., Ambrose K.D., Andrews T.D. Beck S. Nature 425:805-811 (2003).

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