Fatty-acid binding protein 5 (mouse), rabbit polyclonal | Toronto BioScience 12040 product information

product summary

company name :

Toronto BioScience

product type :

antibody

product name :

Fatty-acid binding protein 5 (mouse), rabbit polyclonal

catalog :

12040

quantity :

100 μg

price :

194 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

mouse

application :

western blot

more info or order :

Toronto BioScience product webpage

citations: 4

Reference
Kawaguchi K, Kinameri A, Suzuki S, Senga S, Ke Y, Fujii H. The cancer-promoting gene fatty acid-binding protein 5 (FABP5) is epigenetically regulated during human prostate carcinogenesis. Biochem J. 2016;473:449-61 pubmed publisher
Suojalehto H, Kinaret P, Kilpeläinen M, Toskala E, Ahonen N, Wolff H, et al. Level of Fatty Acid Binding Protein 5 (FABP5) Is Increased in Sputum of Allergic Asthmatics and Links to Airway Remodeling and Inflammation. PLoS ONE. 2015;10:e0127003 pubmed publisher
Smathers R, Petersen D. The human fatty acid-binding protein family: evolutionary divergences and functions. Hum Genomics. 2011;5:170-91 pubmed
Armstrong E, Goswami D, Griffin P, Noy N, Ortlund E. Structural basis for ligand regulation of the fatty acid-binding protein 5, peroxisome proliferator-activated receptor β/δ (FABP5-PPARβ/δ) signaling pathway. J Biol Chem. 2014;289:14941-54 pubmed publisher

product information

Catalog Number :

12040

Product Name :

Fatty-acid binding protein 5 (mouse), rabbit polyclonal

Host Species :

Rabbit

Clonality :

Polyclonal

Conjugation :

Purified

Product Type :

Antibody

Size :

100 μg

List Price (USD) :

194 USD

list of Pubmed id :

21504868, 26614767, 26020772, 24692551

Isotype :

Rabbit IgG

Product Description :

This rabbit polyclonal antibody can detect mouse fatty-acid binding protein 5 (FABP5) by western blot.

SpeciesSummary :

Mouse specificity

Background :

The fatty-acid-binding proteins (FABPs) are a family of carrier proteins for fatty acids and other lipophilic substances such as eicosanoids and retinoids. These proteins are thought to facilitate the transfer of fatty acids between extra- and intracellular membranes. The fatty acid binding protein 4 (FABP-4) and fatty acid binding protein 5(FABP5) are closely related and both are expressed in adipocytes. Mice with targeted disruption of FABP-4 accompany FABP-5 almost completely protect against diet-induced obesity, insulin resistance, dyslipidemia, type 2 diabetes, and fatty liver disease. While mice over expressing FABP5 in adipose have reduced insulin sensitivity.

ALTnames :

Fatty acid binding protein 5 (FABP5) is also known as EFABP; KFABP; E-FABP; PAFABP; PA-FABP.

Immunogen :

Recombinant full-length mouse FABP5 expressed in E.coli.

Specificity :

Mouse

Buffer :

Solution in PBS

Uses :

Western blot - This antibody can be used at 0.5 - 2 μg/mL with the appropriate secondary reagents to detect mouse FABP5.

Application Summary :

Western blot - This antibody can be used at 0.5 - 2 μg/mL with the appropriate secondary reagents to detect mouse FABP5.

Storage :

Store at –20°C. For long-term storage, aliquot and freeze at -70°C. Avoid repeated freeze/defrost cycles.

General References :

[1] Smathers RL, et al. (2011) Hum Genomics; 5(3):170-91. [2] Kawaguchi, et al. (2016) Biochem J; 473(4):449-61. [3] Suojalehto H, et al. PLoS One; 10(5):e0127003. [4] Armstrong EH, et al. (2014) J Biol Chem; 289(21):14941-54.

more info or order :

Toronto BioScience product webpage