Phospho-Akt, rabbit polyclonal anti-Ser473 | Toronto BioScience 11092 product information

product summary

company name :

Toronto BioScience

product type :

antibody

product name :

Phospho-Akt, rabbit polyclonal anti-Ser473

catalog :

11092

quantity :

100 μg

price :

194 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot

more info or order :

Toronto BioScience product webpage

product information

Catalog Number :

11092

Product Name :

Phospho-Akt, rabbit polyclonal anti-Ser473

Host Species :

Rabbit

Clonality :

Polyclonal

Conjugation :

Purified

Product Type :

Antibody

Size :

100 μg

List Price (USD) :

194 USD

list of Pubmed id :

7774014, 9005852, 9497382

Isotype :

Rabbit IgG

Product Description :

This rabbit polyclonal antibody can detect human, mouse and rat phospho-Akt (Ser473) by western blot.

CrossReactivity :

Human, Mouse and Rat

SpeciesSummary :

Human, Mouse, & Rat specificity

Background :

Akt, also known as PKB or Rac, is a critical component of signaling pathways stimulated by various hormones and growth factors, such as insulin. Akt plays an important role in regulating cell metabolism and apoptosis. Akt is activated by phosphorylation at Thr308 by PDK1 and by phosphorylation at Ser473 by mammalian target of rapamycin (mTOR).

ALTnames :

Akt, is also known as AKT1, PKB, RAC, CWS6, PRKBA, PKB-ALPHA, and RAC-ALPHA

Immunogen :

Synthetic phosphopeptide corresponding to residues surrounding Ser473 of mouse Akt.

Specificity :

Human, Mouse, Rat

Buffer :

Solution in PBS

Uses :

Western blot - This antibody can be used as primary antibody to detect phosphor-Akt (Ser473).

Application Summary :

Western blot - This antibody can be used as primary antibody to detect phosphor-Akt (Ser473).

Storage :

Store at –20°C. For long-term storage, aliquot and freeze at -70°C. Avoid repeated freeze/defrost cycles.

General References :

1. PI3K-PKB/Akt pathway. Hemmings BA, Restuccia DF. Cold Spring Harb Perspect Biol. 2012 4(9):a011189 2. Akt, FoxO and regulation of apoptosis. Zhang X, Tang N, Hadden TJ, Rishi AK. Biochim Biophys Acta. 2011 1813(11):1978-86 3. Akt signalling in health and disease. Hers I, Vincent EE, Tavaré JM. Cell Signal. 2011 Oct;23(10):1515-27.

more info or order :

Toronto BioScience product webpage