product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Angiopep-2-Cys
catalog :
8902/5
quantity :
5 mg
price :
189 USD
more info or order :
Tocris Bioscience product webpage
product information
brand :
Tocris
catalog number base :
8902
SKU :
8902/5
product name :
Angiopep-2-Cys
units size :
5 mg
description :
Binds to LRP1 and facilitates receptor-mediated transcytosis of cargo across the BBB
target :
Lipid Nanoparticles
category :
Peptides
purity :
95%
observed molecular weight :
2404.64
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=peptides
details of functionality :
Angiopep-2-Cys is a synthetic peptide able to specifically interact with low-density lipoprotein receptor-related protein 1 (LRP1) receptors present on brain endothelial cells and neurons. Angiopep-2-Cys is a conjugate of Angiopep-2 (Cat. No. 8828) and Cystein, and can be used to functionalize LNPs via thiol-maleimide click chemistry to target LRP1 receptors present on blood-brain barrier (BBB). mRNA LNPs functionalized with Angiopep-2-Cys shows improved transfection efficiency in cultured brain endothelial and neuronal cells, and in vivo , after systemic administration in mice.
top caption :
Binds to LRP1 and facilitates receptor-mediated transcytosis of cargo across the BBB
extended description :
Binds to LRP1 and facilitates receptor-mediated transcytosis of cargo across the BBB
formula :
C107H154N30O32S
formula text :
C107H154N30O32S
cas num :
906480-09-9
USD :
189 USD
product details :
Binds to LRP1 and facilitates receptor-mediated transcytosis of cargo across the BBB
storage :
Store at -20°C
more info or order :
Tocris Bioscience product webpage
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK