product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
8869/2
catalog :
8869/2
quantity :
2 mg
price :
255 USD
more info or order :
Tocris Bioscience product webpage
product information
master code :
8869
SKU :
8869/2
product name :
ArMan
unit size :
2 mg
description :
DC-SIGN ligand used to target dendritic cells
target :
Buffers, Chelators and Reagents
category :
Small Molecules
purity :
98%
observed molecular weight :
379.41
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
ArMan is an aryl mannoside targeting ligand that can be functionalised to the surface of virus like particles (VLPs) via click chemistry. Functionalised particles can be used to target DC-SIGN (dendritic cell-specific intercellular adhesion molecule-3 grabbing nonintegrin) dendritic cells to promote selective coengagement of DC-SIGN and TLR7, resulting in a Th1-type immune response. In vivo , immunization with VLP-ArMan-OvaI/II significantly inhibits tumor growth in a murine melanoma model.
top caption :
DC-SIGN ligand used to target dendritic cells.
extended description :
DC-SIGN ligand used to target dendritic cells
chemical name text :
N-(4-(((2R,3S,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)phenethyl)pent-4-ynamide
formula :
C19H25NO7
formula text :
C19H25NO7
USD :
255 USD
product details :
DC-SIGN ligand used to target dendritic cells
storage :
Store at -20░C
more info or order :
Tocris Bioscience product webpage
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK