product summary
Loading...
company name :
Tocris Bioscience
product type :
chemical
product name :
8835/10
catalog :
8835/10
quantity :
10 mg
price :
225 USD
more info or order :
Tocris Bioscience product webpage
product information
master code :
8835
SKU :
8835/10
product name :
RNB 61
unit size :
10 mg
description :
Highly potent and selective CB2R agonist
target :
Cannabinoid R2/CB2 Agonists
category :
Small Molecules
purity :
97%
observed molecular weight :
481.56
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
RNB 61 is a highly potent and selective cannabinoid CB2 receptor (CB2R) agonist (Ki = 0.57 nM). RNB 61 shows 5000-fold selectivity for hCB2R over hCB1R. In vivo , RNB 61 inhibits the FSK-induced cAMP formation on mouse, rat, and dog CB2Rs (EC50 values ranging from 0.13 to 1.86 nM). RNB 61 has a a peripherally restricted action and exerts a nephroprotective and/or antifibrotic effects in animal models of kidney disease.
top caption :
Highly potent and selective CB2R agonist
extended description :
Highly potent and selective CB2R agonist
chemical name text :
N-[(3E)-5-tert-Butyl-2-(cyclobutylmethyl)-1-methyl-1,2-dihydro-3H-pyrazol-3-ylidene]-2-(2-hydroxy-2-methylpropoxy)-5-(trifluoromethyl)benzamide
formula :
C25H34F3N3O3
formula text :
C25H34F3N3O3
cas num :
1217403-51-4
USD :
225 USD
product details :
Highly potent and selective CB2R agonist
storage :
Store at -20░C
more info or order :
Tocris Bioscience product webpage
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK