8802/5 | Tocris Bioscience 8802/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

8802/5

catalog :

8802/5

quantity :

5 mg

price :

419 USD

more info or order :

Tocris Bioscience product webpage

product information

master code :

8802

SKU :

8802/5

product name :

MPD 2

unit size :

5 mg

description :

SARS-CoV-2 Mpro Degrader (PROTAC )

target :

Active Degraders

category :

Small Molecules

observed molecular weight :

973.13

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

MPD 2 is a SARS-CoV-2 Mpro Degrader (PROTAC ) (DC50 = 296 nM in 293T cells). Mpro degradation is time-dependent and CRBN-mediated. Antiviral in A549-ACE2 cells infected with several SARS-CoV-2 strains (EC50 = 492 nM at delta variant) and against a nirmatrelvir-resistant mutant of SARS-CoV-2, NSP5 E166A (EC50 = 460 nM). . PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license .

top caption :

Application of MPD 2

extended description :

SARS-CoV-2 Mpro Degrader (PROTAC )

chemical name text :

3-((6-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)hexyl)oxy)benzyl ((2S,3R)-3-(tert-butoxy)-1-(((S)-3-cyclohexyl-1-oxo-1-(((S)-1-oxo-3-((S)-2-oxopyrrolidin-3-yl)propan-2-yl)amino)propan-2-yl)amino)-1-oxobutan-2-yl)carbamate

formula :

C51H68N6O13

formula text :

C51H68N6O13

USD :

419 USD

product details :

SARS-CoV-2 Mpro Degrader (PROTAC )

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage