8175/10 | Tocris Bioscience 8175/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

8175/10

catalog :

8175/10

quantity :

10 mg (also 50 mg)

price :

179 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Potent and selective LATS inhibitor; activates YAP signaling

product information

master code :

8175

SKU :

8175/10

product name :

NIBR LTSi

unit size :

10 mg (also 50 mg)

description :

Potent and selective LATS inhibitor; activates YAP signaling

target :

Other Kinase Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

308.39

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

NIBR-LTSi is a potent and selective large tumor suppressor kinase (LATS) inhibitor (IC50 = 1.4 nM). Also activates YAP signaling (EC50 = 1.0 - 2.7 M). Promotes liver organoid formation (EC50 = 0.35 M), hepatocyte proliferation, ISC expansion, and blocks differentiation. NIBR-LTSi is orally bioavailable and suitable for use in vivo and in vitro .

top caption :

Potent and selective LATS inhibitor; activates YAP signaling

extended description :

Potent and selective LATS inhibitor; activates YAP signaling

chemical name text :

N-[4-[(3R)-Piperidin-3-yl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridin-4-amine

formula :

C18H20N4O

formula text :

C18H20N4O

USD :

179 USD

product details :

Potent and selective LATS inhibitor; activates YAP signaling

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage