product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
8131/10
catalog :
8131/10
quantity :
10 mg (also 50 mg)
price :
140 USD
more info or order :
Tocris Bioscience product webpage
product information
master code :
8131
SKU :
8131/10
product name :
OX 04528
unit size :
10 mg (also 50 mg)
description :
Highly potent and selective GPR84 agonist
target :
Orphan 7-TM Receptor Agonists
category :
Small Molecules
purity :
98%
observed molecular weight :
365.28
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
OX 04528 is a highly potent and selective GPR84 agonist. It inhibits cAMP production in CHO cells expressing human GPR84 (EC50 = 6 pM) and shows no -arrestin recruitment. Exhibits selectivity for GPR84 over FFA1, FFA4, and CB2 receptors. In vivo , OX 04528 shows a half-life of 58 minutes following oral dosing at 10 mg/kg in mouse pharmacokinetic studies. OX 04528 is orally bioavailable.
top caption :
Highly potent and selective GPR84 agonist
extended description :
Highly potent and selective GPR84 agonist
chemical name text :
3-(3-(3,5-Bis(trifluoromethyl)phenyl)propyl)-5-hydroxypyridine-1-oxide
formula :
C16H13F6NO2
formula text :
C16H13F6NO2
cas num :
3028055-45-7
USD :
140 USD
product details :
Highly potent and selective GPR84 agonist
storage :
Store at -20░C
more info or order :
Tocris Bioscience product webpage
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK