8122/10 | Tocris Bioscience 8122/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

8122/10

catalog :

8122/10

quantity :

10 mg (also 50 mg)

price :

159 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Potent and selective MST3 kinase binding inhibitor

product information

master code :

8122

SKU :

8122/10

product name :

MR 24

unit size :

10 mg (also 50 mg)

description :

Potent and selective MST3 kinase binding inhibitor

target :

Other Kinase Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

618.38

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

MR 24 is a potent and selective MST3 kinase binding inhibitor with 10 fold selectivity over MST4 (EC50 values from NanoBRET assay are 57 nM and 583 nM for MST3 and MST4 respectively). MR 24 increases the number of cells in G1 phase of cell cycle, is non-cytotoxic and cell permeable. Shows 90% stability over 1 hour in activated liver microsomes in vivo .

top caption :

Potent and selective MST3 kinase binding inhibitor

extended description :

Potent and selective MST3 kinase binding inhibitor

chemical name text :

8-(4-Aminobutyl)-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(1,3-dihydroxypropan-2-ylamino)pyrido[2,3-d]pyrimidin-7-one trihydrochloride

formula :

C26H29ClN6O3.3HCl

formula text :

C26H29ClN6O3.3HCl

USD :

159 USD

product details :

Potent and selective MST3 kinase binding inhibitor

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage