8119/10 | Tocris Bioscience 8119/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

8119/10

catalog :

8119/10

quantity :

10 mg (also 50 mg)

price :

195 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Inhibitor of phosphatidylserine/CEACAM1 binding to Tim-3

product information

master code :

8119

SKU :

8119/10

product name :

ML T7

unit size :

10 mg (also 50 mg)

description :

Inhibitor of phosphatidylserine/CEACAM1 binding to Tim-3

target :

CEACAM-1/CD66a

category :

Small Molecules

purity :

98%

observed molecular weight :

506.34

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

ML T7 is a T cell immunoglobulin and mucin-containing molecule 3 (Tim-3) inhibitor; disrupts phosphatidylserine/CAECAM1 binding to Tim-3 (Kd = 7.0 M and 7.4 M for hTim-3 and mTim-3 respectively). ML T7 promotes cell proliferation, cytokine production and cytotoxicity of OT-I CD8+ cytotoxic T lymphocytes. ML T7 inhibits tumor growth in a syngeneic mouse model of hepatocellular carcinoma, increases NK cell tumor killing activity and DC maturation.

top caption :

Inhibitor of phosphatidylserine/CEACAM1 binding to Tim-3

extended description :

Inhibitor of phosphatidylserine/CEACAM1 binding to Tim-3

chemical name text :

5-(2,4-Dichlorophenyl)-3a,6a-dihydro-3-(4-methylphenyl)spiro[1H-furo[3,4-c]pyrrole-1,2 -[2H]indene]-1 ,3 ,4,6(3H,5H)-tetrone

formula :

C27H17Cl2NO5

formula text :

C27H17Cl2NO5

cas num :

459789-75-4

USD :

195 USD

product details :

Inhibitor of phosphatidylserine/CEACAM1 binding to Tim-3

alt names :

antigen CD66, BGP1, BGP-1, BGP1BGPBiliary glycoprotein 1, BGPI, Biliary Glycoprotein 1, biliary glycoprotein adhesion molecule, carcinoembryonic antigen-related cell adhesion molecule 1, carcinoembryonic antigen-related cell adhesion molecule 1 (biliaryglycoprotein), CD366, CD66a, CD66a antigen, Cea-1, CEACAM1, HAVcr-2, HAVCR2, Hv-1, Hv-2, KIM-3, MHVR, SPTCL, TIM3, TIMD3

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage