8079/5 | Tocris Bioscience 8079/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

8079/5

catalog :

8079/5

quantity :

5 mg

price :

399 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

NSD2 Degrader (PROTAC )

product information

master code :

8079

SKU :

8079/5

product name :

MS 159

unit size :

5 mg

description :

NSD2 Degrader (PROTAC )

target :

Active Degraders

category :

Small Molecules

purity :

98%

observed molecular weight :

828.84

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

MS 159 is a nuclear receptor binding SET structural domain protein 2 (NSD2) Degrader (DC50 = 5.2 M, Dmax = 82%). Also degrades IKZF3 and IKZF1. Comprises an NSD2 binding moiety joined by a linker to a cereblon E3 ligase ligand. Inhibits proliferation of KMS11 and H929 tumor cells. Bioavailable in vivo . . PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

top caption :

NSD2 Degrader (PROTAC )

extended description :

NSD2 Degrader (PROTAC )

chemical name text :

N-Cyclopropyl-N-(4-((5-(3-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)acetamido)propoxy)pyridin-2-yl)-carbamoyl)benzyl)-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-carboxamide

formula :

C43H40N8O10

formula text :

C43H40N8O10

cas num :

3031353-59-7

USD :

399 USD

product details :

NSD2 Degrader (PROTAC )

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage