8070/10 | Tocris Bioscience 8070/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

8070/10

catalog :

8070/10

quantity :

10 mg

price :

299 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Potent NDUFS7 antagonist

product information

master code :

8070

SKU :

8070/10

product name :

DX3-213B

unit size :

10 mg

description :

Potent NDUFS7 antagonist

target :

Oxidative Phosphorylation Inhibitors

category :

Small Molecules

purity :

97%

observed molecular weight :

478.57

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

DX3-213B is a potent oxidative phosphorylation (OXPHOS) complex I (also known as NDUFS7) antagonist (IC50 = 3.6 nM). DX3-213B impairs ATP generation (IC50 = 11 nM) and inhibits the proliferation of MIA PaCa-2 cells (IC50 = 9 nM) in galactose-containing media. In vivo , DX3-213B significantly delays tumor growth in a syngeneic mouse model of pancreatic cancer. DX3-213B is orally bioavailable.

top caption :

Potent NDUFS7 antagonist

extended description :

Potent NDUFS7 antagonist

chemical name text :

(4,4-Difluoro-1-piperidinyl)[(3R)-1-[[4-[(1-methylethyl)sulfonyl]phenyl]sulfonyl]-3-piperidinyl]methanone

formula :

C20H28F2N2O5S2

formula text :

C20H28F2N2O5S2

cas num :

2749555-66-4

USD :

299 USD

product details :

Potent NDUFS7 antagonist

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage