product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
8047/50
catalog :
8047/50
quantity :
50 mg
price :
389 USD
more info or order :
Tocris Bioscience product webpage
product information
master code :
8047
SKU :
8047/50
product name :
JP-2-196 alkyne
unit size :
50 mg
description :
RNF126 chemical handle; alkyne functionalized version of JP-2-196 (Cat. No. 8046).
target :
Molecular Glues
category :
Small Molecules
purity :
95%
observed molecular weight :
312.37
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
JP-2-196 alkyne is a covalent RNF126 chemical handle that binds to several other RING E3 ubiquitin ligases including RNF14, RNF40, RNF219, MID2, and LRSAM1. By facilitating E3 ligase recruitment, JP-2-196 alkyne induces proteasomal degradation of diverse target proteins. It serves as a modular scaffold for the design and synthesis of molecular glue degraders. JP-2-196 alkyne is an alkyne functionalized version of JP-2-196 (Cat. No. 8046).
top caption :
RNF126 chemical handle; alkyne functionalized version of JP-2-196 (Cat. No. 8046).
extended description :
RNF126 chemical handle; alkyne functionalized version of JP-2-196 (Cat. No. 8046).
chemical name text :
1-(4-Methoxyphenyl)-4-[4-(2-propyn-1-yl)-1-piperazinyl]-2-butene-1,4-dione
formula :
C18H20N2O3
formula text :
C18H20N2O3
cas num :
2901113-25-3
USD :
389 USD
product details :
RNF126 chemical handle; alkyne functionalized version of JP-2-196 (Cat. No. 8046).
storage :
Store at -20░C
more info or order :
Tocris Bioscience product webpage
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK