product summary
Loading...
company name :
Tocris Bioscience
product type :
chemical
product name :
8046/50
catalog :
8046/50
quantity :
50 mg
price :
319 USD
more info or order :
Tocris Bioscience product webpage
product information
master code :
8046
SKU :
8046/50
product name :
JP-2-196
unit size :
50 mg
description :
RNF126 chemical handle
target :
Molecular Glues
category :
Small Molecules
purity :
95%
observed molecular weight :
310.78
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
JP-2-196 is a covalent RNF126 chemical handle that binds to several other RING E3 ubiquitin ligases including RNF14, RNF40, RNF219, MID2, and LRSAM. By facilitating E3 ligase recruitment, JP-2-196 induces proteasomal degradation of diverse target proteins. It serves as a modular scaffold for the design and synthesis of molecular glue degraders.
top caption :
RNF126 chemical handle
extended description :
RNF126 chemical handle
chemical name text :
1-(4-Methoxyphenyl)-4-(1-piperazinyl)-2-butene-1,4-dione hydrochloride
formula :
C15H18N2O3.HCl
formula text :
C15H18N2O3.HCl
USD :
319 USD
product details :
RNF126 chemical handle
storage :
Store at -20░C
more info or order :
Tocris Bioscience product webpage
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK