8040/5 | Tocris Bioscience 8040/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

8040/5

catalog :

8040/5

quantity :

5 mg

price :

419 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

-synuclein PROTAC Degrader

product information

master code :

8040

SKU :

8040/5

product name :

a-Synuclein Degrader 2b

unit size :

5 mg

description :

-synuclein Degrader (PROTAC )

target :

Active Degraders

category :

Small Molecules

purity :

98%

observed molecular weight :

767.8

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

-Synuclein Degrader 2b is a selective -synuclein Degrader (PROTAC ) (DC50 = 7.5 Dmax = 89%). Comprises the probe molecule sery308, joined by a linker to a pomalidomide E3 ligase ligand. Activates both proteasomal and lysosomal degradation pathways. Protects SH-SY5Y cells from -synuclein-induced cytotoxicity. Cell permeable. . PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

top caption :

-synuclein PROTAC Degrader

extended description :

-synuclein Degrader (PROTAC )

chemical name text :

2-[[3-[5-(1,3-Benzodioxol-5-yl)-1H-pyrazol-3-yl]phenyl]amino]-N-[2-[2-[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]ethoxy]ethyl]acetamide

formula :

C39H41N7O10

formula text :

C39H41N7O10

cas num :

2781922-42-5

USD :

419 USD

product details :

-synuclein Degrader (PROTAC )

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage