8029/5 | Tocris Bioscience 8029/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

8029/5

catalog :

8029/5

quantity :

5 mg

price :

269 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Interleukin 1 Receptor Associated Kinase 1 (IRAK1) PROTAC

product information

master code :

8029

SKU :

8029/5

product name :

JNJ 1013

unit size :

5 mg

description :

Interleukin 1 Receptor Associated Kinase 1 (IRAK1) Degrader (PROTAC )

target :

Active Degraders

category :

Small Molecules

purity :

98%

observed molecular weight :

878.06

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

JNJ 1013 is a potent interleukin 1 receptor associated kinase 1 (IRAK1) Degrader (PROTAC DC50 = 3 nM; Dmax = 96%). In ABC DLBCL cell lines with MyD88 L265P mutation, JNJ 1013 potently inhibits IRAK1 downstream signaling pathways, induces apoptosis, and shows strong anti-proliferative effects. . PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license .

top caption :

Interleukin 1 Receptor Associated Kinase 1 (IRAK1) PROTAC

extended description :

Interleukin 1 Receptor Associated Kinase 1 (IRAK1) Degrader (PROTAC )

chemical name text :

N-(4-(4-(2-(((S)-1-((2S,4R)-4-Hydroxy-2-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-2-oxoethoxy)piperidin-1-yl)-2-methoxyphenyl)-6-(1H-pyrazol-5-yl)picolinamide

formula :

C46H55N9O7S

formula text :

C46H55N9O7S

cas num :

2597343-08-1

USD :

269 USD

product details :

Interleukin 1 Receptor Associated Kinase 1 (IRAK1) Degrader (PROTAC )

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage