8021/2 | Tocris Bioscience 8021/2 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

8021/2

catalog :

8021/2

quantity :

2 mg

price :

529 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

IAP-VHL Degrader

product information

master code :

8021

SKU :

8021/2

product name :

CST 626

unit size :

2 mg

description :

Potent pan IAP Degrader (PROTAC )

target :

Active Degraders

category :

Small Molecules

purity :

98%

observed molecular weight :

1103.43

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

CST 626 is a potent IAP Degrader (PROTAC ) (DC50 values at 16 hours are 0.7 nM, 2.4 nM and 6.2 nM at XIAP, cIAP1 and cIAP2 respectively; Dmax = 90-99%). Reduces cell viability in some cell types, including SUDHL6 and MOLM13 (IC50 values are 16 nM and 21 nM respectively). . PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

top caption :

IAP-VHL Degrader

extended description :

Potent pan IAP Degrader (PROTAC )

chemical name text :

(2S,4S)-1-((S)-2-Cyclohexyl-2-((S)-2-(methylamino)propanamido)acetyl)-4-(3-((5-(((S)-1-((2S,4R)-4-hydroxy-2-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-5-oxopentyl)oxy)phenoxy)-N-((R)-1,2,3,

formula :

C61H82N8O9S

formula text :

C61H82N8O9S

cas num :

3033993-13-1

USD :

529 USD

product details :

Potent pan IAP Degrader (PROTAC )

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage