8015/1 | Tocris Bioscience 8015/1 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

8015/1

catalog :

8015/1

quantity :

1 mg

price :

437 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Asialoglycoprotein receptor ligands with PEG3 linker and azide group for onward chemistry

product information

master code :

8015

SKU :

8015/1

product name :

tri-GalNAc-PEG3-Azide

unit size :

1 mg

description :

Asialoglycoprotein receptor ligands with PEG3 linker and azide group for onward chemistry

target :

Degrader Building Blocks

category :

Small Molecules

purity :

90%

observed molecular weight :

1644.83

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

tri-GalNAc-PEG3-Azide is a functionalized asialoglycoprotein receptor (ASGPR) ligand for lysosomal targeting chimera (LYTAC) research and development; each molecule incorporates three ASGPR ligands with a PEG3 linker and azide group reactive handle ready for conjugation. Upon binding to the ASGPR, tri-GalNAc conjugates are efficiently internalized via ASGPR-mediated endocytosis. tri-GalNAc conjugation can be employed as a strategy to effectively deliver cargo such as RNA or Cas9 complexes in a cell-specific manner to hepatocytes. Can be used to generate LYTACs, or labeled with dye for tissue imaging.

top caption :

Asialoglycoprotein receptor ligands with PEG3 linker and azide group for onward chemistry

extended description :

Asialoglycoprotein receptor ligands with PEG3 linker and azide group for onward chemistry

formula :

C70H125N13O31

formula text :

C70H125N13O31

cas num :

2925590-71-0

USD :

437 USD

product details :

Asialoglycoprotein receptor ligands with PEG3 linker and azide group for onward chemistry

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage