8010/5 | Tocris Bioscience 8010/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

8010/5

catalog :

8010/5

quantity :

5 mg

price :

269 USD

more info or order :

Tocris Bioscience product webpage

product information

master code :

8010

SKU :

8010/5

product name :

SB 24011

unit size :

5 mg

description :

Inhibitor of STING-TRIM29 interaction; increases cellular STING levels

target :

Protein Dimerizers

category :

Small Molecules

purity :

98%

observed molecular weight :

614.7

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

SB 24011 is an inhibitor of STING-TRIM29 interaction (IC50 = 3.85 M in vitro ). SB 24011 binds to STING and inhibits TRIM29-E3 ligase interaction to increase cellular STING levels. In syngeneic mouse models, SB 24011 dose-dependently reduces CT26 and B16F10 tumor volumes when co-admistered with cGAMP .

top caption :

Inhibitor of STING-TRIM29 interaction; increases cellular STING levels

extended description :

Inhibitor of STING-TRIM29 interaction; increases cellular STING levels

chemical name text :

4-[(2R)-3,4-Dihydro-4-[(4-hydroxyphenyl)methyl]-5-[(4-methoxyphenyl)methyl]-2-(1-methylethyl)-3-oxo-1(2H)-pyrazinyl]-3-nitro-N-[[(2S)-tetrahydro-2-furanyl]methyl]benzamide

formula :

C34H38N4O7

formula text :

C34H38N4O7

cas num :

1497415-41-4

USD :

269 USD

product details :

Inhibitor of STING-TRIM29 interaction; increases cellular STING levels

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage