7978/10 | Tocris Bioscience 7978/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7978/10

catalog :

7978/10

quantity :

10 mg

price :

349 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Potent and selective TRPA1 antagonist. Brain penetrant and orally bioavailable

product information

master code :

7978

SKU :

7978/10

product name :

BAY 390

unit size :

10 mg

description :

Potent and selective TRPA1 antagonist. Brain penetrant and orally bioavailable

target :

TRPA1 Blockers

category :

Small Molecules

purity :

98%

observed molecular weight :

277.26

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

BAY 390 is a potent and selective transient receptor potential ankyrin 1 (TRPA1) antagonist (IC50 values are 16, 63 and 82 nM for hTRPA1 FLIPR, rTRPA1 FLIPR and hTRPA1 Ephys, respectively). In vivo , BAY 390 exhibits efficacy in rat models of inflammatory and neuropathic pain. BAY 390 is orally bioavailable and brain penetrant. Suitable to use as an in vitro or in vivo probe to investigate the roles of TRPA1 in models of acute, inflammatory, and neuropathic pain.

top caption :

Potent and selective TRPA1 antagonist. Brain penetrant and orally bioavailable

extended description :

Potent and selective TRPA1 antagonist. Brain penetrant and orally bioavailable

chemical name text :

(1R,2R)-2-[(4-Fluorophenyl)amino]-1-(trifluoromethyl)cyclohexanol

formula :

C13H15F4NO

formula text :

C13H15F4NO

cas num :

2741956-55-6

USD :

349 USD

product details :

Potent and selective TRPA1 antagonist. Brain penetrant and orally bioavailable

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage