7959/5 | Tocris Bioscience 7959/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7959/5

catalog :

7959/5

quantity :

5 mg

price :

649 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Glucagon-like Peptide-1 Receptor (GLP1-R) molecular glue agonist

product information

master code :

7959

SKU :

7959/5

product name :

LSN 3318839

unit size :

5 mg

description :

Glucagon-like peptide-1 receptor (GLP1-R) positive allosteric modulator

target :

Glucagon-Like Peptide 1 Receptor Modulators

category :

Small Molecules

purity :

98%

observed molecular weight :

480.39

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

LSN 3318839 is a potent glucagon-like peptide-1 receptor (GLP1-R) positive allosteric modulator (EC50 = 14 nM). Acts as a molecular glue to stabilize peptide ligand and GLP1 receptor interaction. Potentiates activity of GLP-1 (7-36) (Cat. No. 2082) and the low-affinity metabolite GLP-1 (9-36) (Cat. No. 3266). LSN 3318839 alone or in combination with Sitagliptin (Cat. No. 6816) lowers glucose levels in animal models of diabetes. LSN 3318839 is orally bioavailable.

top caption :

Glucagon-like Peptide-1 Receptor (GLP1-R) molecular glue agonist

extended description :

Glucagon-like peptide-1 receptor (GLP1-R) positive allosteric modulator

chemical name text :

(R)-2-(2-(1-((R)-1-(2,6-Dichloro-3-cyclopropylphenyl)ethyl)-1H-imidazo[4,5-c]pyridin-6-yl)phenyl)propanoic acid

formula :

C26H23Cl2N3O2

formula text :

C26H23Cl2N3O2

cas num :

2764704-18-7

USD :

649 USD

product details :

Glucagon-like peptide-1 receptor (GLP1-R) positive allosteric modulator

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage