chemical

7955/10U

7955/10U

10 ug

445 USD

7955/10U

CELT-426

10 ug

Potent and partially selective hD2 dopamine receptor fluorescent antagonist

Dopamine D2 R/DRD2

Small Molecules

95%

1615.85

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CELT-426 is a potent and partially selective fluorescent hD2 dopamine receptor antagonist (Ki values are 89.3 nM, 194.8 nM, and 263.6 nM for D2, D3, and D4 dopamine receptors respectively in radioligand binding assay). CELT-426 can be used as a fluorescent dopamine receptor probe for fluorescence binding assays, live cell imaging, flow cytometry, and fluorescence polarization assays. It is a suitable replacement for GPCR radiolabeling ligands. Excitation and emission maxima ( ) are 560 and 571 nm, respectively. Wavelengths are compatible with use as an acceptor dye in TR-FRET assays, together with the CoraFluor 1 (Cat. No. 7920) TR-FRET donor. . Add 62 L of assay buffer containing 1% of DMSO to obtain a 100 M stock solution, and use 250 nM as working concentration.

Application of CELT-426 (100 nM) in CHO cells.

Flow Cytometry

Potent and partially selective hD2 dopamine receptor fluorescent antagonist

445 USD

Potent and partially selective hD2 dopamine receptor fluorescent antagonist

D(2) dopamine receptor, D2DR, D2R, Dopamine D2 receptor, Dopamine D2R, dopamine receptor D2, dopamine receptor D2 isoform, DRD2, seven transmembrane helix receptor

Store at -20░C