7936/10 | Tocris Bioscience 7936/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7936/10

catalog :

7936/10

quantity :

10 mg (also 50 mg)

price :

135 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Ac-Cys-NHMe CAS No. 10061-65-1 Building block for the lysine acylation using conjugating enzymes (LACE) technique

product information

master code :

7936

SKU :

7936/10

product name :

Ac-Cys-NHMe

unit size :

10 mg (also 50 mg)

description :

Building block for the lysine acylation using conjugating enzymes (LACE) technique

target :

Unnatural Amino Acids

category :

Small Molecules

observed molecular weight :

176.23

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Ac-Cys-NHMe is a non-canonical amino acid that is an essential building block for lysine acylation using conjugating enzymes (LACE) technique. LACE is a chemoenzymatic approach that uses an E2 small ubiquitin-like modifier (SUMO)-conjugating enzyme, Ubc9, to conjugate peptide thioesters containing a C-terminal ubiquitin-derived sequence (LRLRGG) to a lysine residue located in a recognition sequence (IKQE) on a protein via an isopeptide bond. Ac-Cys-NHMe can be reacted with a peptide hydrazide to form a reactive peptide thioester, which is the substrate for Ubc9. LACE enables the site-specific modification of proteins at lysine residues to allow attachment of biochemical probes such as fluorophores to proteins or to engineer proteins for site-specific delivery.

top caption :

Building block for the lysine acylation using conjugating enzymes (LACE) technique

extended description :

Building block for the lysine acylation using conjugating enzymes (LACE) technique

chemical name text :

(2R)-2-(Acetylamino)-3-mercapto-N-methylpropanamide

formula :

C6H12N2O2S

formula text :

C6H12N2O2S

cas num :

10061-65-1

USD :

135 USD

product details :

Building block for the lysine acylation using conjugating enzymes (LACE) technique

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage