7898/10 | Tocris Bioscience 7898/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7898/10

catalog :

7898/10

quantity :

10 mg

price :

86 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Inhibits the interaction between the serotonin transporter (SERT) and neuronal nitric oxide synthase (nNOS)

product information

master code :

7898

SKU :

7898/10

product name :

ZZL 7

unit size :

10 mg

description :

Inhibitor of SERT and nNOS interaction

target :

SLC6A4/5-HTTLPR

category :

Small Molecules

purity :

98%

observed molecular weight :

244.29

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

ZZL-7 is a fast-acting antidepressant that enhances 5-HT (serotonin) signaling in forebrain circuits. ZZL-7 disrupts the interaction between the 5-HT transporter (SERT) and neuronal nitric oxide synthase (nNOS) in the dorsal raphe nucleus (DRN), reduces extracellular 5-HT concentration and downregulates 5-HT1A receptor auto-activity in the DRN. This reduced auto-inhibition enables increase in firing frequency of serotonergic neurons in the DRN and increases in 5-HT release in the medial hippocampus. ZZL-7 readily crosses the blood-brain barrier.

top caption :

Inhibitor of the interaction between the 5-HT transporter (SERT) and neuronal nitric oxide synthase (nNOS)

extended description :

Inhibitor of SERT and nNOS interaction

chemical name text :

N-Acetyl-L-alanyl-L-valine methyl ester

formula :

C11H20N2O4

formula text :

C11H20N2O4

cas num :

99141-91-0

USD :

86 USD

product details :

Inhibitor of SERT and nNOS interaction

alt names :

5HT transporter, 5-HT Transporter, 5-HTT, 5HTTLPR, 5-HTTLPR, hSERT, HTT5-hydroxytryptamine transporter, Na+/Cl- dependent serotonin transporter, NOS1, OCD1, Serotonin Transporter 1, SERT, sodium-dependent serotonin transporter, solute carrier family 6 (neurotransmitter transporter, serotonin), member 4,5-HTTLPR, Solute carrier family 6 member 4,5HTT

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage