7886/5 | Tocris Bioscience 7886/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7886/5

catalog :

7886/5

quantity :

5 mg

price :

349 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Potent and selective HER2 targeting PROTAC

product information

master code :

7886

SKU :

7886/5

product name :

HER2 PROTAC CH7C4

unit size :

5 mg

description :

Potent and selective HER2 targeting Degrader (PROTAC )

target :

Active Degraders

category :

Small Molecules

purity :

98%

observed molecular weight :

910.05

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

HER2 PROTAC CH7C4 is a potent and selective HER2 (also called ErbB-2) targeting Degrader (PROTAC ) (DC50 = 69 nM; Dmax = 96%). Inhibits BT-474 cell proliferation (IC50 = 47 nM) and xenograft growth. Comprises a Tucatinib (Cat. No. 7640) analog, joined by a linker to a CRBN E3 ligase ligand. . PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

top caption :

Potent and selective HER2 targeting PROTAC

extended description :

Potent and selective HER2 targeting Degrader (PROTAC )

chemical name text :

5-((7-(4-(3-((4-((4-([1,2,4]Triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenyl)amino)-6-methoxyquinazolin-7-yl)oxy)propyl)piperazin-1-yl)heptyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

formula :

C49H55N11O7

formula text :

C49H55N11O7

cas num :

2897640-93-4

USD :

349 USD

product details :

Potent and selective HER2 targeting Degrader (PROTAC )

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage