7876/10 | Tocris Bioscience 7876/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7876/10

catalog :

7876/10

quantity :

10 mg (also 50 mg)

price :

150 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

PanK Activator

product information

master code :

7876

SKU :

7876/10

product name :

PZ 3022

unit size :

10 mg (also 50 mg)

description :

PanK Activator

target :

Enzyme Activators

category :

Small Molecules

purity :

98%

observed molecular weight :

347.42

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

PZ 3022 is a potent allosteric pantothenate kinase (PanK) activator (EC50=5.3 nM for PanK3). In a mouse model of propionic acidemia, treatment with PZ 3022 increases hepatic CoASH and C2-CoA, and decreases C3-CoA, improving intracellular C3:C2-CoA ratio and plasma C3:C2-carnitine ratios. PZ 3022 is orally bioavailable.

top caption :

PanK Activator

extended description :

PanK Activator

chemical name text :

6-[4-[2-(4-Cyclopropylphenyl)acetyl]-1-piperazinyl]-3-pyridazinecarbonitrile

formula :

C20H21N5O

formula text :

C20H21N5O

cas num :

2170608-85-0

USD :

150 USD

product details :

PanK Activator

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage