7851/10 | Tocris Bioscience 7851/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7851/10

catalog :

7851/10

quantity :

10 mg (also 50 mg)

price :

135 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Selective NTAQ1 Degrader (PROTAC )

product information

master code :

7851

SKU :

7851/10

product name :

EM 12-FS

unit size :

10 mg (also 50 mg)

description :

Molecular glue; induces degradation of NQAT1

target :

Molecular Glues

category :

Small Molecules

purity :

95%

observed molecular weight :

342.3

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

EM12-FS is a selective N-terminal glutamine amidohydrolase 1 (NTAQ1) Degrader. In MOLT4 cells, it downregulates NTAQ1 via cereblon-mediated degradation (IC50 = 256 nM). Requires covalent His353 engagement to recruit and degrade NTAQ1.

top caption :

Selective NTAQ1 Degrader (PROTAC )

extended description :

Molecular glue; induces degradation of NQAT1

chemical name text :

3-[6-[(Fluorosulfonyl)oxy]-1,3-dihydro-1-oxo-2H-isoindol-2-yl]-2,6-piperidinedione

formula :

C13H11FN2O6S

formula text :

C13H11FN2O6S

cas num :

2839138-44-0

USD :

135 USD

product details :

Molecular glue; induces degradation of NQAT1

alt names :

Selective NTAQ1 degrader

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage