7841/50 | Tocris Bioscience 7841/50 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7841/50

catalog :

7841/50

quantity :

50 mg

price :

76 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Imipramine hydrochloride CAS No. 113-52-0 Potent inhibitor of serotonin and noradrenalin transporters; promotes immunostimulatory tumor microenvironment

product information

master code :

7841

SKU :

7841/50

product name :

Imipramine hydrochloride

unit size :

50 mg

description :

Potent inhibitor of 5-HT and noradrenalin transporters; promotes immunostimulatory tumor microenvironment

target :

Autophagy-related Compounds

category :

Small Molecules

purity :

98%

observed molecular weight :

316.87

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Imipramine hydrochloride is a potent tricyclic antidepressant; inhibits 5-HT and noradrenalin transporters (Ki values = 1.3-20 nM and 20-142 nM respectively). Increases autophagy, both alone and in combination with VEGF inhibitors or Temozolomide (Cat. No. 2706), to reduce the progression of glioma and slow the proliferation of other tumors. Reprograms tumor-associated macrophages from immunosuppressive to immunostimulatory via histamine receptor inhibition.

top caption :

Potent inhibitor of 5-HT and noradrenalin transporters; promotes immunostimulatory tumor microenvironment

extended description :

Potent inhibitor of 5-HT and noradrenalin transporters; promotes immunostimulatory tumor microenvironment

chemical name text :

5-(3-Dimethylaminopropyl)-10,11-dihydro-5H-dibenz[b,f]azepine hydrochloride

formula :

C19H24N2.HCl

formula text :

C19H24N2.HCl

cas num :

113-52-0

USD :

76 USD

product details :

Potent inhibitor of 5-HT and noradrenalin transporters; promotes immunostimulatory tumor microenvironment

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage