product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
7832/1
catalog :
7832/1
quantity :
1 mg
price :
199 USD
more info or order :
image
image 1 :
Tocris Bioscience 7832/1 image 1
Peptide inhibitor of YAP signaling
product information
master code :
7832
SKU :
7832/1
product name :
TAT-PDHPS1
unit size :
1 mg
description :
YAP inhibitor
target :
YAP1
category :
Peptides
purity :
95%
observed molecular weight :
3744.32
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=peptides
details of functionality :
TAT-PDHPS1 is a YAP inhibitor (Yes-associated protein inhibitor). It comprises the endogenous peptide PDHPS1 and the cell-penetrating peptide sequence TAT. PDHPS1 binds to protein phosphatase 2 phosphatase activator (PTPA), which activates protein phosphatase 2A (PP2A). This activation leads to the phosphorylation of YAP and the suppression of YAP-targeted genes. TAT-PDHPS1 inhibits the proliferation of ovarian cancer cells in vitro and ovarian tumor growth in a subcutaneous xenograft mouse model.
top caption :
Peptide inhibitor of YAP signaling
extended description :
YAP inhibitor
formula :
C156H280N62O45
formula text :
C156H280N62O45
USD :
199 USD
product details :
YAP inhibitor
alt names :
65 kDa Yes-associated protein, COB1, HEPTP, HLPR, LRP, PP2CA, PPP2CA, Protein Yorkie Homolog, PTPase-alpha, PTPRA, PTPRL2, RP-C, Transcriptional Coactivator YAP1, YAP, YAP1-2gamma, YAP2, YAP2L, YAP65, YAP65yes-associated protein 2, Yes Associated Protein, Yes-Associated Protein, Yes-associated protein 1, Yes-associated protein 1, 65kDa, yes-associated protein beta, yes-associated protein delta, Yes-Associated Protein YAP65 Homolog, YKI, Yorkie Homolog
storage :
Store at -20░C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK