product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
ML 162
catalog :
7821/10
quantity :
10 mg (also 50 mg)
price :
168 USD
more info or order :
Tocris Bioscience product webpage
image
image 1 :
Tocris Bioscience 7821/10 image 1
ML 162 CAS No. 1035072-16-2 Inhibits glutathione peroxidase (GPX4); induces ferroptosis
product information
brand :
Tocris
catalog number base :
7821
SKU :
7821/10
product name :
ML 162
units size :
10 mg (also 50 mg)
description :
Inhibits glutathione peroxidase (GPX4); induces ferroptosis
target :
Ferroptosis Activators
category :
Small Molecules
purity :
98%
observed molecular weight :
477.41
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
ML 162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor. It induces ferroptosis in vivo . It is selectively lethal to mutant RAS oncogene-expressing cell lines (IC50 = 25 and 578 nM for HRASG12V-expressing and wild-type BJ fibroblasts, respectively).
top caption :
Inhibits glutathione peroxidase (GPX4); induces ferroptosis
extended description :
Inhibits glutathione peroxidase (GPX4); induces ferroptosis
chemical name text :
2-[(Chloroacetyl)(3-chloro-4-methoxyphenyl)amino]-N-(2-phenylethyl)-2-thien-2-ylacetamide
formula :
C23H22Cl2N2O3S
formula text :
C23H22Cl2N2O3S
cas num :
1035072-16-2
USD :
168 USD
product details :
Inhibits glutathione peroxidase (GPX4); induces ferroptosis
storage :
Store at -20°C
more info or order :
Tocris Bioscience product webpage
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK