7821/10 | Tocris Bioscience 7821/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7821/10

catalog :

7821/10

quantity :

10 mg (also 50 mg)

price :

168 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

ML 162 CAS No. 1035072-16-2 Inhibits glutathione peroxidase (GPX4); induces ferroptosis

product information

master code :

7821

SKU :

7821/10

product name :

ML 162

unit size :

10 mg (also 50 mg)

description :

Inhibits glutathione peroxidase (GPX4); induces ferroptosis

target :

Glutathione Peroxidase 4/GPX4

category :

Small Molecules

purity :

98%

observed molecular weight :

477.41

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

ML 162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor. It induces ferroptosis in vivo . It is selectively lethal to mutant RAS oncogene-expressing cell lines (IC50 = 25 and 578 nM for HRASG12V-expressing and wild-type BJ fibroblasts, respectively).

top caption :

Inhibits glutathione peroxidase (GPX4); induces ferroptosis

extended description :

Inhibits glutathione peroxidase (GPX4); induces ferroptosis

chemical name text :

2-[(Chloroacetyl)(3-chloro-4-methoxyphenyl)amino]-N-(2-phenylethyl)-2-thien-2-ylacetamide

formula :

C23H22Cl2N2O3S

formula text :

C23H22Cl2N2O3S

cas num :

1035072-16-2

USD :

168 USD

product details :

Inhibits glutathione peroxidase (GPX4); induces ferroptosis

alt names :

EC 1.11.1, EC 1.11.1.12, Glutathione peroxidase 4, glutathione peroxidase 4 (phospholipid hydroperoxidase), GPx-4, GPX4, GSHPx-4, MCSP, PHGPx, PHGPxsnGPx, phospholipid hydroperoxidase, phospholipid hydroperoxide glutathione peroxidase, mitochondrial, snGPx, snPHGPx, sperm nucleus glutathione peroxidase

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage