7808/2 | Tocris Bioscience 7808/2 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7808/2

catalog :

7808/2

quantity :

2 mg

price :

339 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Potent NLRP3 inflammasome inhibitor

product information

master code :

7808

SKU :

7808/2

product name :

NDT 30805

unit size :

2 mg

description :

Potent NLRP3 inflammasome inhibitor

target :

Inflammasomes Inhibitors

category :

Small Molecules

purity :

95%

observed molecular weight :

414.53

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

NDT 30805 is a potent NLRP3 inflammasome inhibitor. Inhibits IL-1 release in peripheral blood mononuclear cell assay, ASC speck assay and in whole blood (IC50 values are 13 nM, 34 nM and 1500 nM). Inhibits Nigericin (Cat. No. 4312) and ATP-induced IL-1 release. Soluble and uncharged at physiological pH.

top caption :

Potent NLRP3 inflammasome inhibitor

extended description :

Potent NLRP3 inflammasome inhibitor

chemical name text :

2-((1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)amino)-5-(pyridin-2-ylmethyl)-[1,2,4]triazolo[1,5-a]pyrimidine-7(4H)-thione

formula :

C23H22N6S

formula text :

C23H22N6S

USD :

339 USD

product details :

Potent NLRP3 inflammasome inhibitor

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage