7807/1 | Tocris Bioscience 7807/1 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7807/1

catalog :

7807/1

quantity :

1 mg (also 5 mg)

price :

212 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Hh-Ag1.5 CAS No. 612542-14-0 Potent and high affinity Smo receptor agonist

product information

master code :

7807

SKU :

7807/1

product name :

Hh-Ag1.5

unit size :

1 mg (also 5 mg)

description :

Potent and high affinity Smo receptor agonist

target :

Smoothened

category :

Small Molecules

purity :

98%

observed molecular weight :

526.04

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Hh-Ag1.5 is a potent and high affinity Smoothened (Smo) receptor agonist (EC50 = 1 nM; Ki values are 0.5 and 2.3 nM respectively, in a [3H]SAG-1.3 and [3H]Cyclopamine binding assay). It is used in protocols for the chemical reprogramming of mouse embryonic fibroblasts into neural stem cells. Also induces differentiation of hiPSCs into skin-derived precursor cells, spinal motor neurons and spinal sensory neurons.

top caption :

Potent and high affinity Smo receptor agonist

extended description :

Potent and high affinity Smo receptor agonist

chemical name text :

3-Chloro-4,7-difluoro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]benzo[b]thiophene-2-carboxamide

formula :

C28H26ClF2N3OS

formula text :

C28H26ClF2N3OS

cas num :

612542-14-0

USD :

212 USD

product details :

Potent and high affinity Smo receptor agonist

alt names :

bnb, CRJS, FZD11, Gx, Protein Gx, SMO, SMOH, SMOHseven transmembrane helix receptor, smoothened (Drosophila) homolog, smoothened homolog, smoothened homolog (Drosophila)

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage