7794/10 | Tocris Bioscience 7794/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7794/10

catalog :

7794/10

quantity :

10 mg (also 50 mg)

price :

89 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Selective mitochondrial citrate transporter (SLC25A1) inhibitor

product information

master code :

7794

SKU :

7794/10

product name :

CTPI 2

unit size :

10 mg (also 50 mg)

description :

Selective mitochondrial citrate transporter (SLC25A1) inhibitor

target :

Other Ion Pump/Transporter Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

356.74

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

CTPI 2 is a selective mitochondrial citrate transporter (SLC25A1) inhibitor with a KD of 3.5 M. CTPI 2 inhibits the proliferation of H1299 cells in a SLC25A1-dependent manner. It also re-sensitizes T1, T2, and T4 cells to Cisplatin (Cat. No. 2251). CTPI 2 inhibits tumor growth in in vivo models of non-small cell lung cancer (NSCLC). In high-fat diet fed mice CTPI 2 regulates glycolysis, prevents steatohepatitis and normalizes glucose tolerance and insulin sensitivity. CTPI 2 influences the inflammatory pathway by inhibiting IL-6 and TNF production and M1 macrophage polarization.

top caption :

Selective mitochondrial citrate transporter (SLC25A1) inhibitor

extended description :

Selective mitochondrial citrate transporter (SLC25A1) inhibitor

chemical name text :

2-[[(4-Chloro-3-nitrophenyl)sulfonyl]amino]benzoic acid

formula :

C13H9ClN2O6S

formula text :

C13H9ClN2O6S

cas num :

68003-38-3

USD :

89 USD

product details :

Selective mitochondrial citrate transporter (SLC25A1) inhibitor

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage