7791/10 | Tocris Bioscience 7791/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7791/10

catalog :

7791/10

quantity :

10 mg

price :

183 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Induces growth and proliferation of pancreatic islet cells, murine totipotent stem cells, GABAergic neurons and hippocampal neurons

product information

master code :

7791

SKU :

7791/10

product name :

WS 6

unit size :

10 mg

description :

Induces growth and proliferation of pancreatic islet cells, murine totipotent stem cells, GABAergic neurons and hippocampal neurons

target :

Compounds for Stem Cell Proliferation and Renewal

category :

Small Molecules

purity :

98%

observed molecular weight :

568.59

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

WS 6 induces growth and proliferation of cultured islet and cells in vitro (EC50 = 0.28 M at cells). Inhibits growth of FLT3- ITD+ AML and K562 CML cells (IC50 values are 0.24 nM and 40.48 nM, respectively). Reduces blood glucose in an animal model of type 1 diabetes. In combination with TTNPB (Cat. No. 0761) and 1-azakenpaullone, WS 6 induces and maintains murine totipotent stem cells. In an animal model of depression WS 6 induces dendrite complexity, enhances hippocampal neurogenesis, increases GABAergic neurons and GABA expression, and displays antidepressant and anxiolytic activity. WS 6 is predicted to be a receptor tyrosine kinase inhibitor.

top caption :

Induces growth and proliferation of pancreatic islet cells, murine totipotent stem cells, GABAergic neurons and hippocampal neurons

extended description :

Induces growth and proliferation of pancreatic islet cells, murine totipotent stem cells, GABAergic neurons and hippocampal neurons

chemical name text :

4-[[6-[(Cyclopropylcarbonyl)amino]-4-pyrimidinyl]oxy]-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]benzeneacetamide

formula :

C29H31F3N6O3

formula text :

C29H31F3N6O3

cas num :

1421227-53-3

USD :

183 USD

product details :

Induces growth and proliferation of pancreatic islet cells, murine totipotent stem cells, GABAergic neurons and hippocampal neurons

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage