7780/25 | Tocris Bioscience 7780/25 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7780/25

catalog :

7780/25

quantity :

25 mg

price :

541 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

beta-GalNAc-PEG4-Azide CAS No. 879004-92-9 Asialoglycoprotein receptor ligand with PEG4 linker and azide group for onward chemistry

product information

master code :

7780

SKU :

7780/25

product name :

beta-GalNAc-PEG4-Azide

unit size :

25 mg

description :

Asialoglycoprotein receptor ligand with PEG4 linker and azide group for onward chemistry

target :

ASGR1/ASGPR1

category :

Small Molecules

purity :

95%

observed molecular weight :

422.44

url print :

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details of functionality :

-GalNAc-PEG4-Azide is a functionalized asialoglycoprotein receptor (ASGPR) ligand for lysosomal targeting chimera (LYTAC) research and development; incorporates a single ASGPR ligand with a PEG4 linker and azide group reactive handle ready for conjugation. It can be used as a building block for multivalent compounds to enhance ASGPR binding. Upon binding to ASGPR, -GalNAc conjugates are efficiently internalized via ASGPR-mediated endocytosis. -GalNAc conjugation can be employed as a strategy to effectively deliver cargo such as RNA or Cas9 complexes in a cell-specific manner to hepatocytes. Can be used to generate LYTACs, or labeled with dye for tissue imaging.

top caption :

Asialoglycoprotein receptor ligand with PEG4 linker and azide group for onward chemistry

extended description :

Asialoglycoprotein receptor ligand with PEG4 linker and azide group for onward chemistry

chemical name text :

2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethyl 2-(acetylamino)-2-deoxy- -D-galactopyranoside

formula :

C16H30N4O9

formula text :

C16H30N4O9

cas num :

879004-92-9

USD :

541 USD

product details :

Asialoglycoprotein receptor ligand with PEG4 linker and azide group for onward chemistry

alt names :

ASGPR, ASGPR 1, ASGP-R 1, ASGPR1, ASGPR2, asialoglycoprotein receptor 1, CLEC4H1, CLEC4H1ASGPR1, CLEC4H2, C-type lectin domain family 4 member H1, HBXBP, Hepatic lectin H1, HL-1, MHL1, RHL1

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage