7745/5 | Tocris Bioscience 7745/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7745/5

catalog :

7745/5

quantity :

5 mg

price :

319 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Potent and selctive BRAFV600E Degrader (PROTAC )

product information

master code :

7745

SKU :

7745/5

product name :

CST 905

unit size :

5 mg

description :

Potent and selective BRAFV600E Degrader (PROTAC )

target :

Active Degraders

category :

Small Molecules

purity :

98%

observed molecular weight :

1025.2

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

CST 905 is a potent and selective BRAFV600E Degrader (PROTAC ) (DC50 = 18 nM). CST 905 comprises a ligand for the von Hippel Lindau (VHL) E3 ligase joined by a linker to a PLX-derived ligand. Unlike other BRAFV600E Degraders, CST 905 does not activate ERK. . B-Raf antibody validated for Simple Western (automated Western) instruments and Western Blot also available: Catalog # AF3424 . . PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

top caption :

Potent and selctive BRAFV600E Degrader (PROTAC )

extended description :

Potent and selective BRAFV600E Degrader (PROTAC )

chemical name text :

(2S,4R)-1-((S)-2-(2-(4-(4-(3-(3-((N-Ethyl-N-methylsulfamoyl)amino)-2,6-difluorobenzoyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl)piperazin-1-yl)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide

formula :

C51H58F2N10O7S2

formula text :

C51H58F2N10O7S2

USD :

319 USD

product details :

Potent and selective BRAFV600E Degrader (PROTAC )

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage