product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
7718/359U
catalog :
7718/359U
quantity :
359 ug
price :
363 USD
more info or order :
image
image 1 :
Tocris Bioscience 7718/359U image 1
Cat.No. 7718 - 3 ,2 -cGAMP sodium salt C20H22N10Na2O13P2
product information
master code :
7718
SKU :
7718/359U
product name :
3',2'-cGAMP sodium salt
unit size :
359 ug
description :
Induces expression of STING and STING-related genes; antiviral
target :
STING/TMEM173
category :
Small Molecules
purity :
98%
observed molecular weight :
718.38
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
3 ,2 -cGAMP sodium salt is a second messenger in the antiviral immune response in Drosophila melanogaster and in bacteria. 3 ,2 -cGAMP is selective for Drosophila stimulator of interferon genes (dSTING); induces expression of STING and STING-related genes. After injection of drosophila C virus dsRNA into Drosophila, 3 ,2 -cGAMP activates STING-dependent antiviral immunity in vivo , reduces viral RNA load and increases survival. In bacteria 3 ,2 -cGAMP activates DNA degradation of As Cap5 and Ll Cap5.
top caption :
Induces expression of STING and STING-related genes; antiviral
extended description :
Induces expression of STING and STING-related genes; antiviral
chemical name text :
3 ,2 -Cyclic guanosine monophosphate-adenosine monophosphate sodium salt
formula :
C20H22N10Na2O13P2
formula text :
C20H22N10Na2O13P2
USD :
363 USD
product details :
Induces expression of STING and STING-related genes; antiviral
alt names :
endoplasmic reticulum IFN stimulator, Endoplasmic reticulum interferon stimulator, ERIS, FLJ38577, hMITA, hSTING, Mediator of IRF3 activation, MITA, mitochondrial mediator of IRF3 activation, MPYS, NET23, N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner, SAVI, Stimulator of interferon genes protein, stimulator of interferon protein, sting, STING-beta, TMEM173, transmembrane protein 173
storage :
Store at -20░C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK