Masitinib | Tocris Bioscience 7705/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Masitinib

catalog :

7705/10

quantity :

10 mg (also 50 mg)

price :

116 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7705 - Masitinib C28H30N6OS CAS No. 790299-79-5

product information

brand :

Tocris

catalog number base :

7705

SKU :

7705/10

product name :

Masitinib

units size :

10 mg (also 50 mg)

description :

Potent colony-stimulating factor 1 receptor (CSF-1R) tyroine kinase inhibitor

target :

Additional RTK Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

498.64

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Masitinib is a potent inhibitor of the tyrosine kinase receptor colony-stimulating factor 1R (CSF-1R) (IC50 = 90 nM). It is also an NLRP3 inflammasome activator. Masitinib additionally inhibits the proteolytic activity of SARS-CoV-2 main protease (Mpro) and blocks viral replication, as well as acting as a PDGFR / inhibitor. In vivo , Masitinib ameliorates cognitive impairment in transgenic mice model of Alzheimer s disease, and slows disease progression in a rat model of amyotrophic lateral sclerosis (ALS). Orally bioavailable.

top caption :

Potent colony-stimulating factor 1 receptor (CSF-1R) tyroine kinase inhibitor

extended description :

Potent colony-stimulating factor 1 receptor (CSF-1R) tyroine kinase inhibitor

chemical name text :

4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-thiazolyl]amino]phenyl]benzamide

formula :

C28H30N6OS

formula text :

C28H30N6OS

cas num :

790299-79-5

USD :

116 USD

product details :

Potent colony-stimulating factor 1 receptor (CSF-1R) tyroine kinase inhibitor

storage :

Store at -20Â°C

more info or order :

Tocris Bioscience product webpage