7699/5 | Tocris Bioscience 7699/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7699/5

catalog :

7699/5

quantity :

5 mg

price :

430 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Mitochondrial targeting AUTAC

product information

master code :

7699

SKU :

7699/5

product name :

AUTAC4

unit size :

5 mg

description :

Mitochondrial targeting AUTAC Degrader

target :

Active Degraders

category :

Small Molecules

purity :

98%

observed molecular weight :

869.97

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

AUTAC4 is an autophagy-targeting chimera targeting mitochondria. Comprises p -fluorobenzyl guanine joined by a PEG linker to a 2-phenylindole-3-glyoxyaminde ligand for the translocator protein on the outer mitochondrial membrane. It delivers a guanine tag to the mitochondrial membrane and promotes mitophagy of damaged mitochondria. In Down syndrome cells, AUTAC4 degrades impaired mitochondria and promotes the generation of functionally normal mitochondria.

top caption :

Mitochondrial targeting AUTAC Degrader

extended description :

Mitochondrial targeting AUTAC Degrader

chemical name text :

N-[(16R)-16-[[[2-Amino-9-[(4-fluorophenyl)methyl]-6,9-dihydro-6-oxo-1H-purin-8-yl]thio]methyl]-15,18-dioxo-4,7,10-trioxa-14,17-diazanonadec-1-yl]- -oxo-2-phenyl-1H-indole-3-acetamide

formula :

C43H48FN9O8S

formula text :

C43H48FN9O8S

cas num :

2267315-04-6

USD :

430 USD

product details :

Mitochondrial targeting AUTAC Degrader

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage