7696/10 | Tocris Bioscience 7696/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7696/10

catalog :

7696/10

quantity :

10 mg (also 50 mg)

price :

170 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7696 - Selpercatinib C29H31N7O3 CAS No. 2152628-33-4

product information

master code :

7696

SKU :

7696/10

product name :

Selpercatinib

unit size :

10 mg (also 50 mg)

description :

Potent and selective RET inhibitor

target :

Ret

category :

Small Molecules

purity :

98%

observed molecular weight :

525.6

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Selpercatinib, is a potent and selective receptor tyrosine kinase RET inhibitor (EC50 = 4 nM). It shows 100-fold selectivity for 95% of 228 purified kinase domains in radiometric assays. In vitro , it inhibits proliferation of cancer cell lines containing RET mutations or gene fusions. In vivo , it inhibits tumor growth in diverse RET mouse models. Selpercatinib is orally bioavailable.

top caption :

Potent and selective RET inhibitor

extended description :

Potent and selective RET inhibitor

chemical name text :

6-(2-Hydroxy-2-methylpropoxy)-4-[6-[6-[(6-methoxy-3-pyridinyl)methyl]-3,6-diazabicyclo[3.1.1]hept-3-yl]-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-carbonitrile

formula :

C29H31N7O3

formula text :

C29H31N7O3

cas num :

2152628-33-4

USD :

170 USD

product details :

Potent and selective RET inhibitor

alt names :

CDHF12MTC1, CDHR16, EC 2.7.10, Hirschsprung disease 1, Hirschsprung disease), MEN2A, MEN2B, multiple endocrine neoplasia and medullary thyroid carcinoma 1, ret proto-oncogene, RET transforming sequence

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage