7692/10 | Tocris Bioscience 7692/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7692/10

catalog :

7692/10

quantity :

10 mg (also 50 mg)

price :

216 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 7692 - C26-A6 C14H13ClN4O3S CAS No. 1341030-00-9

product information

master code :

7692

SKU :

7692/10

product name :

C26-A6

unit size :

10 mg (also 50 mg)

description :

Disrupts MTDH and SND1 interaction, enhances immune surveillance

target :

Cell Adhesion Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

352.79

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

C26-A2 inhibits the interaction between MTDH and SND1 by blocking the SND1 pocket. C26-A2 disrupts MTDH-SND1 complex-induced reduction in tumor antigen presentation and T cell infiltration; enhancing immune surveillance and sensitivity to anti-PD-1 therapy in metastatic breast cancer mouse models. C26-A6 suppresses tumor growth (IC50 = 12.3 M) and metastasis and enhances chemotherapy sensitivity in triple-negative breast cancer (TNBC) mouse models.

top caption :

Disrupts MTDH and SND1 interaction, enhances immune surveillance

extended description :

Disrupts MTDH and SND1 interaction, enhances immune surveillance

chemical name text :

5-Chloro-2-methoxy-N-(2-methyl[1,2,4]triazolo[1,5-a]pyridin-8-yl)benzenesulfonamide

formula :

C14H13ClN4O3S

formula text :

C14H13ClN4O3S

cas num :

1341030-00-9

USD :

216 USD

product details :

Disrupts MTDH and SND1 interaction, enhances immune surveillance

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage