product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
7681/10
catalog :
7681/10
quantity :
10 mg
price :
137 USD
more info or order :
image
image 1 :
Tocris Bioscience 7681/10 image 1
Cat.No. 7681 - Mandi C23H22ClNO4 CAS No. 374726-62-2
product information
master code :
7681
SKU :
7681/10
product name :
Mandi
unit size :
10 mg
description :
Highly efficient chemical inducer of proximity (CIP)
target :
Protein Dimerizers
category :
Small Molecules
purity :
98%
observed molecular weight :
411.88
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Mandi is a chemical inducer of proximity (CIP) in vivo and in vitro (EC50 = 0.43 M in a luciferase gene expression assay). Mandi induces complex formation between PYR1Mandi, a mutant of Abscisic Acid (Cat. No. 6554) receptor PYR1, and Abscisic Acid insensitive (ABI). Mandi may be used to induce protein colocalization and interaction. It is non-toxic, orthogonal to mammalian processes and other CIPs, and highly cell permeable.
top caption :
Highly efficient chemical inducer of proximity (CIP)
extended description :
Highly efficient chemical inducer of proximity (CIP)
chemical name text :
4-Chloro-N-[2-[3-methoxy-4-(2-propyn-1-yloxy)phenyl]ethyl]- -(2-propyn-1-yloxy)benzeneacetamide
formula :
C23H22ClNO4
formula text :
C23H22ClNO4
cas num :
374726-62-2
USD :
137 USD
product details :
Highly efficient chemical inducer of proximity (CIP)
storage :
Store at -20░C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK